Protein name:
Mdm2-binding protein (mMTBP) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with MDM2.
Function:
May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells.
Subcellular Location:
N/A
Protein Attributes:
50:
MDRYLLLVTW | REGKFRSVAG | GEIEPGTEAT | SLESTDKQPD | LTATNIYHLL |
100:
KRSISDSIHP | DDSTFPACSV | GGTPHSRKWF | FAVQAICGFY | QFCSSDWQEI |
150:
HFDAEKDKIE | DVLQANIEEC | QSAVECFEED | DSNSRESLPL | ADLYEESAEN |
200:
LHQLSDKLPA | PGRAMIDIIL | LPSDKDPPKL | KECLPIVGAL | KHLKEWHSAK |
250:
VIIAGSYCEI | NCQKIAEYLS | ASVVPLEEFR | NAIDPRELWR | GEIQMRERKF |
300:
GFEISFPEFC | LKGVTPTNVS | AYNLNTCFLA | KKIASSKVFH | YYGPALEFVQ |
350:
MIKLSDLPSC | YMSDIEFELE | VTGHCTRQNS | MLLLEQISSL | CGKVGALFVL |
400:
PCTVSNVLIP | PPSQLASRKW | KEYMAKKPKT | ISVPDVAVKG | EFSGYHLLLQ |
450:
GMGKRKCRAT | LLHSASQING | SFALSVIHGK | MKTKAGEARP | SFPFDFSSLP |
500:
RFSEEQVLQR | EKQLASFQVL | ALKECLKRRK | AANQPEAFSA | DELKSLLALT |
550:
RERFLGHFDV | LPTEAALAQT | DTVKAAGVVN | DDGTVEPYSS | SLMETNPLEW |
600:
PERHVLQNLE | TSEKAKQKMR | TGSLPRSSEQ | LLGHKEGPRD | SLTLLDAKEL |
650:
LKYFTSDGLP | VGDLQPLHIQ | RGEKPFVLTP | ELSPGKLQVL | PFEKASECHY |
700:
HGIEYCLDDQ | KALERDGGFS | ELQSRLIRYE | TQTTCTRDSF | PVPTVLSPLP |
750:
SPAVLSEPQS | VPEGEALQGE | LRTEVSGLKR | RSKDPSCLYP | QKRLTRSESS |
800:
DCLPSQASCN | SNHHHHTGKP | RKPQAERCVS | GLPLPGREAS | KDTSKTSSGQ |
850:
KRAHESKSSK | QMKESRSQKH | TRMLKEVVKD | TLKRHHITEA | HESFTACSQR |
894:
LFDISKFYLK | DLKTSRGLFE | EMKKTANNNV | VQVIEWVVEK | MSKK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse mMTBP
ELISA Kit for Mouse mMTBP
Polyclonal Antibody for Mouse mMTBP
Polyclonal Antibody for Mouse mMTBP
Monoclonal Antibody for Mouse mMTBP
Monoclonal Antibody for Mouse mMTBP
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH MDM2;TISSUE SPECIFICITY
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Science309:1559-1563(2005)
[
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[
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[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
strain :
C57BL/6J .
strain :
NOD .
tissue :
Aorta .
tissue :
Embryo .
tissue :
Thymus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N .
tissue :
Limb .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE